Structures
62 structures I have helped solve and deposit in the Protein Data Bank since 2002. See also my publications, and the explorer for the technical details of every entry.
Featured
3ZE3Integral membrane diacylglycerol kinase (DgkA)
A small membrane kinase solved with both synchrotron and XFEL radiation.
2YEVcaa3-type cytochrome c oxidase
A respiratory complex IV with its own fused cytochrome c domain.
3PDSβ2 adrenergic receptor with an irreversible agonist
A G-protein-coupled receptor caught in complex with a covalently bound agonist.
5J36Beak and feather disease virus capsid
The shell of a virus that kills parrots, including the endangered orange-bellied parrot.
6BW9Hendra and Nipah virus W proteins with importin α
How two deadly bat-borne viruses hijack the machinery that carries proteins into the cell nucleus.
1W9MHybrid cluster protein
An iron protein with a strange iron–sulfur–oxygen cluster, and the heart of my PhD.
5KMRType II NADH dehydrogenase
A respiratory enzyme that bacteria need and we don't, and so a possible antibiotic target.
6Y84SARS-CoV-2 main protease
The main protease of the virus that causes COVID-19, with an empty active site.
1GYOCytochrome c3 from Desulfovibrio gigas
The first structure I refined and wrote up, from the bacterium Jean LeGall discovered.
2Y5MLinear gramicidin D in lipidic cubic phase
Showing that small membrane peptides can be solved in meso.
4AFKAlgE alginate transporter
The pore that Pseudomonas aeruginosa uses to export alginate for its biofilms.
6Q45F1-ATPase from Fusobacterium nucleatum
The catalytic head of the ATP-making motor from a disease-causing bacterium, and how it keeps itself in check.
2VKRZinc-containing ferredoxin from Acidianus ambivalens
A small protein from a hot-spring archaeon with seven iron atoms in two clusters, plus a zinc, all intact.
Pictures are my own renders, made with UCSF ChimeraX.
All entries
Each code links to the entry at PDBe (EMBL-EBI); the explorer has resolution, cell, R factors, electron density and more.
2023
2021
- 7RG6Importin alpha2 in complex with ORF4B Bat coronavirus HKU5 · 2.1 Ådetails
- 7RG5Importin alpha3 in complex with p50 NLS · 2.15 Ådetails
- 7RG4Importin alpha2 in complex with p50 NLS · 2.6 Ådetails
- 7RG3Importin alpha2 in complex with MERS ORF4B R37A mutant · 2 Ådetails
- 7RG2Importin alpha2 in complex with MERS ORF4B R33A mutant · 2 Ådetails
- 7RG1Importin alpha2 in complex with MERS ORF4B H26A mutant · 1.85 Ådetails
- 7RG0Importin alpha2 in complex with MERS ORF4B R24A mutant · 2 Ådetails
- 7RFZImportin alpha 2 in complex with MERS ORF4B NLS peptide · 1.95 Ådetails
- 7RFYImportin alpha3 in complex with MERS ORF4B · 2.5 Ådetails
- 7RFXImportin alpha2 in complex with MERS ORF4B · 2.1 Ådetails
2020
- 6WX9SOX2 bound to Importin-alpha 5 · 2.8 Ådetails
- 6WX8SOX2 bound to Importin-alpha 3 · 2.3 Ådetails
- 6WX7SOX2 bound to Importin-alpha 2 · 2.7 Ådetails
- 6YB7SARS-CoV-2 main protease with unliganded active site (2019-nCoV, coronavirus disease 2019, COVID-19). · 1.25 Ådetails
- 6Y84SARS-CoV-2 main protease with unliganded active site (2019-nCoV, coronavirus disease 2019, COVID-19) · 1.39 Ådetails
- 6VZ6Methanococcoides burtonii cytochrome b5 domain protein (WP 011499504.1) · 2.1 Ådetails
2019
- 6PZNPutative SDR from Acinetobacter baumannii Crystal Form 2 · 2 Ådetails
- 6PZMPutative SDR from Acinetobacter baumannii Crystal Form 1 · 2.1 Ådetails
- 6Q45F1-ATPase from Fusobacterium nucleatum · 3.6 Ådetails
- 6NZXHadesarchaea YNP_N21 cytochrome b5 domain protein (KUO41884.1) · 1.9 Ådetails
- 6NRPPutative short-chain dehydrogenase/reductase (SDR) from Acinetobacter baumannii · 1.9 Ådetails
2018
- 6BWBHendra virus W protein C-terminus in complex with Importin alpha 3 crystal form 3 · 2.3 Ådetails
- 6BWAHendra virus W protein C-terminus in complex with Importin alpha 3 crystal form 2 · 2.2 Ådetails
- 6BW9Hendra virus W protein C-terminus in complex with Importin alpha 3 crystal form 1 · 1.6 Ådetails
- 6BW1Hendra virus W protein C-terminus in complex with Importin alpha 1 · 2.2 Ådetails
- 6BW0Nipah virus W protein C-terminus in complex with Importin alpha 1 · 2.1 Ådetails
- 6BVZImportin alpha 3 in cargo free state · 2.3 Ådetails
- 6BVVNipah virus W protein C-terminus in complex with Importin alpha 3 · 2.3 Ådetails
- 6BVTImportin alpha 1 in cargo free state · 2.5 Ådetails
- 6BDOStructure of bacterial type II NADH dehydrogenase from Caldalkalibacillus thermarum complexed with a quinone inhibitor HQNO at 2.8A resolution · 2.8 Ådetails
2017
- 5WEDStructure of bacterial type II NADH dehydrogenase from Caldalkalibacillus thermarum at 2.15A resolution · 2.15 Ådetails
- 5KMSThe structure of type II NADH dehydrogenase from Caldalkalibacillus thermarum complexed with NAD+ at 2.5 angstrom resolution. · 2.5 Ådetails
- 5KMRThe structure of type II NADH dehydrogenase from Caldalkalibacillus thermarum complexed with NAD+ at 3.0 angstrom resolution. · 3 Ådetails
- 5KMQThe structure of I379E variant of type II NADH dehydrogenase from Caldalkalibacillus thermarum · 2.7 Ådetails
- 5KMPThe structure of G164E variant of type II NADH dehydrogenase from Caldalkalibacillus thermarum · 3.2 Ådetails
2016
2015
2013
- 4B61In meso structure of alginate transporter, AlgE, from Pseudomoas aeruginosa, PAO1. Crystal form 3. · 2.402 Ådetails
- 4AZLIn meso structure of alginate transporter, AlgE, from Pseudomoas aeruginosa, PAO1, crystal form 2. · 2.8 Ådetails
- 3ZE5Crystal structure of the integral membrane diacylglycerol kinase - delta4 · 3.101 Ådetails
- 3ZE4Crystal structure of the integral membrane diacylglycerol kinase - wild-type · 3.702 Ådetails
- 3ZE3Crystal structure of the integral membrane diacylglycerol kinase - delta7 · 2.05 Ådetails
- 4AFKIn meso structure of alginate transporter, AlgE, from Pseudomonas aeruginosa, PAO1 · 1.897 Ådetails
2012
- 3ZQ8STRUCTURE OF LINEAR GRAMICIDIN D OBTAINED USING TYPE I CRYSTALS GROWN IN A monovaccenin LIPID CUBIC PHASE · 1.7 Ådetails
- 2YEVStructure of caa3-type cytochrome oxidase · 2.36 Ådetails
2011
- 2Y6NStructure of linear gramicidin d obtained using type i crystals grown in a 8.8 monoacylglycerol lipid cubic phase. · 1.26 Ådetails
- 2Y5MStructure of linear gramicidin d obtained using type i crystals grown in a 7.7 monoacylglycerol lipid cubic phase. · 1.08 Ådetails
- 3PDSIrreversible Agonist-Beta2 Adrenoceptor Complex · 3.5 Ådetails
2010
2008
2007
2005
2003
- 1UPXThe crystal structure of the Hybrid Cluster Protein from Desulfovibrio desulfuricans containing molecules in the oxidized and reduced states. · 1.25 Ådetails
- 1OA1Reduced hybrid cluster protein (hcp) from desulfovibrio vulgaris hildenborough structure at 1.55a resolution using synchrotron radiation. · 1.55 Ådetails
- 1OA0Reduced hybrid cluster protein from desulfovibrio desulfuricans x-ray structure at 1.25a resolution · 1.25 Ådetails
2002
Withdrawn entries, replaced by newer depositions: 6OV4 → 6PZM, 6OV5 → 6PZN.